{"id":742,"date":"2023-12-15T09:45:20","date_gmt":"2023-12-15T07:45:20","guid":{"rendered":"https:\/\/eventdk.nordiske-medier.dk\/pack-point-nordic\/?page_id=742"},"modified":"2026-09-02T09:49:35","modified_gmt":"2026-09-02T07:49:35","slug":"speakers","status":"publish","type":"page","link":"https:\/\/nmevents.se\/bioprocessing-stockholm\/speakers\/","title":{"rendered":"Speakers"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"742\" class=\"elementor elementor-742\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bac3737 e-flex e-con-boxed e-con e-parent\" data-id=\"bac3737\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8f33627 e-flex e-con-boxed e-con e-child\" data-id=\"8f33627\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-34f6731 elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"34f6731\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 20-03-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Note: Speaker recruitment is currently ongoing. The list of speakers is subject to continuous updates and additions.\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-31a8edd e-flex e-con-boxed e-con e-parent\" data-id=\"31a8edd\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dac23b6 elementor-widget elementor-widget-menu-anchor\" data-id=\"dac23b6\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 20-03-2024 *\/\nbody.elementor-page .elementor-widget-menu-anchor{margin-bottom:0}<\/style>\t\t<div id=\"JohanRockberg\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4a94764 e-flex e-con-boxed e-con e-parent\" data-id=\"4a94764\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d253619 e-con-full e-flex e-con e-child\" data-id=\"d253619\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-47ba209 e-flex e-con-boxed e-con e-child\" data-id=\"47ba209\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1be7716 elementor-widget elementor-widget-image\" data-id=\"1be7716\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 20-03-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2024\/02\/2sssz9nmkw77hahb_500_500.jpg\" class=\"attachment-full size-full wp-image-1037\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2024\/02\/2sssz9nmkw77hahb_500_500.jpg 500w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2024\/02\/2sssz9nmkw77hahb_500_500-300x300.jpg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2024\/02\/2sssz9nmkw77hahb_500_500-150x150.jpg 150w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-452f220 elementor-widget elementor-widget-text-editor\" data-id=\"452f220\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0ac6a8a e-con-full e-flex e-con e-child\" data-id=\"0ac6a8a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9621c18 elementor-widget elementor-widget-heading\" data-id=\"9621c18\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 20-03-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Moderator<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-80c8489 elementor-widget elementor-widget-text-editor\" data-id=\"80c8489\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Johan Rockberg<br \/><\/strong>Professor in Antibody Technology and Directed Evolution<br \/>KTH Royal Institute of Technology<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e00a88c elementor-widget elementor-widget-text-editor\" data-id=\"e00a88c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><em><strong>Johan Rockberg is Professor of Antibody Engineering and Directed Evolution at KTH &#8211; Royal Institute of Technology in Stockholm, Sweden. He holds a Master of Science in Chemical Engineering from KTH with studies in Bioinformatics and Biotechnology at the University of Sydney, and completed his doctoral degree in 2008 at KTH with a thesis on bioinformatical and combinatorial methods for the generation and characterization of monospecific antibodies.<\/strong><\/em><\/p><p><em>Today, his research group works at the intersection of synthetic and systems biology, with a particular focus on protein and cell line engineering for novel curative gene therapies and their scalable bioproduction, including AAV-based vectors, protein vaccine, bispecific therapeutics for cancer and autoimmune diseases.\u00a0<\/em><\/p><p><em>Routed in protein engineering and synthetic biology his lab leverage engineering of both the drug candidate, using in-house combinatorial libraries, deep sequencing and screening platforms, as well as mammalian cell lines for their production using directed and evolutionary methods.<\/em><\/p><p><em>Rockberg is Director of GeneNova, a Vinnova-funded innovation milieu in precision health with a budget of 114 MSEK, and is PI in several major national centers including CellNova and AdBIOPRO focused on advanced continuous manufacturing.\u00a0<\/em><\/p><p><em>He is co-founder of 7 spinn-out companies \u2014 Atlas Antibodies, Atlas Therapeutics, Abclon Inc. (Seoul), Labrock AB, StrikePharma AB, Auweai AB and AareBio AB\u2014 spanning antibody reagents, cancer immunotherapy, CAR-T gene therapy and Precision Patient Segmentation through machine learning.\u00a0<\/em><\/p><p><em>He is a co-founder of the Korean company Abclon, listed on the KOSDAQ exchange, currently developing CAR-T and antibody therapies, including an antibody combination in global Phase 3 trials for gastric and breast cancer.<\/em><\/p><p><em>He is an elected member of the Royal Swedish Academy of Engineering Sciences and recipient of the 2024 Biotech Builders Award and the 2021 SwedenBIO Life Science Star Award. With over 26,000 citations and publications in journals including Science, Nature Methods, Nature Communications and PNAS, Rockberg represents a combination of scientific depth, institutional leadership and entrepreneurship.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-759df82 e-flex e-con-boxed e-con e-parent\" data-id=\"759df82\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d30f0b2 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"d30f0b2\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 20-03-2024 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100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-539e64c e-flex e-con-boxed e-con e-parent\" data-id=\"539e64c\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8f1da3f elementor-widget elementor-widget-menu-anchor\" data-id=\"8f1da3f\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"HenrikIhre\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b4351aa e-flex e-con-boxed e-con e-parent\" data-id=\"b4351aa\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d8994d9 e-con-full e-flex e-con e-child\" data-id=\"d8994d9\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-a20e34b e-flex e-con-boxed e-con e-child\" data-id=\"a20e34b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba8cd70 elementor-widget elementor-widget-image\" data-id=\"ba8cd70\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1254\" height=\"1254\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Henrik-Ihre.png\" class=\"attachment-full size-full wp-image-2169\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Henrik-Ihre.png 1254w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Henrik-Ihre-300x300.png 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Henrik-Ihre-1024x1024.png 1024w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Henrik-Ihre-150x150.png 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Henrik-Ihre-768x768.png 768w\" sizes=\"(max-width: 1254px) 100vw, 1254px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-71eead6 elementor-widget elementor-widget-text-editor\" data-id=\"71eead6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5404541 e-con-full e-flex e-con e-child\" data-id=\"5404541\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a892c50 elementor-widget elementor-widget-heading\" data-id=\"a892c50\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Designing Process Intensification in the mAb Capture Step for the MSAT Handoff \u2014 Not Just PD Success<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-081093d elementor-widget elementor-widget-text-editor\" data-id=\"081093d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Henrik Ihre<br \/><\/strong>PhD, Distinguished Fellow Resins and Technologies<br \/>Cytiva<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ec1c4ac elementor-widget elementor-widget-text-editor\" data-id=\"ec1c4ac\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"x_x_MsoNormal\"><span lang=\"EN-US\" data-olk-copy-source=\"MessageBody\">Process intensification of the protein A capture step is widely pursued to shorten cycle time, reduce footprint, lower cost of goods, and improve sustainability in monoclonal antibody (mAb) manufacturing. Yet processes optimized solely for process development (PD) success may not always translate into robust, transferable GMP processes.\u00a0<\/span>\u00a0<\/p><p class=\"x_x_MsoNormal\"><span lang=\"EN-US\">Industry survey data across PD, clinical, and commercial stages reveal that current capture cycle times consistently exceed ideal targets by 20\u201330%, while upstream titers continue to climb placing growing pressure on the downstream capture step. This presentation examines how PD, MSAT, and Manufacturing stakeholders can align on shared objectives such as speed, predictability, process robustness, and operational simplicity when intensifying protein A chromatography. Here we discuss when and how to apply intensification strategies across the development lifecycle.<\/span>\u00a0<\/p><p><em><strong>Henrik Ihre<\/strong> has been appointed Distinguished Fellow in 2025 at Cytiva and has a with a specific knowledge and background in the Downstream purification of biopharmaceuticals since 26 years back in time.<\/em><\/p><p><em>Henrik joined legacy Amersham Pharmacia Biotech in August 2000, following its acquisition by GE Healthcare in 2004. His career has been devoted to the design and development of several purification products enabling the manufacturing of life changing drugs on the market.\u00a0 Henrik started as a Senior Scientist in the R&amp;D chromatography resin department and later transferred into the role of Product Manager for several key products such as the Protein A portfolio. For more than ten year he headed and expanded the custom consumables organization. During his time in the custom consumable\u2019s organization more than 30 key products where brought to the market which now are a part of the Cytiva downstream offering.<\/em><\/p><p><em>His journey started in Sweden with a Ph.D. in synthetic organic polymer chemistry from the Royal Academy of Engineering (KTH) in 1998. After his graduate studies he spent two years as a Post Doc graduate at UC Berkeley in California, USA working on improved drug delivery systems of cytotoxins before he moved back to Sweden in 2000 joining legacy Amersham Pharmacia Biotech. Henrik is a Swedish citizen living in Stockholm working from the Cytiva office in Uppsala.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8d9ea5e e-flex e-con-boxed e-con e-parent\" data-id=\"8d9ea5e\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01f231e elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"01f231e\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7c8d03e e-flex e-con-boxed e-con e-parent\" data-id=\"7c8d03e\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8ff15d2 elementor-widget elementor-widget-menu-anchor\" data-id=\"8ff15d2\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"MeiLingLim\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0dd034b e-flex e-con-boxed e-con e-parent\" data-id=\"0dd034b\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ebff28d e-con-full e-flex e-con e-child\" data-id=\"ebff28d\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-da653db e-flex e-con-boxed e-con e-child\" data-id=\"da653db\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5e1b4b9 elementor-widget elementor-widget-image\" data-id=\"5e1b4b9\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2140\" height=\"2140\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim.jpg\" class=\"attachment-full size-full wp-image-2177\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim.jpg 2140w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim-300x300.jpg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim-1024x1024.jpg 1024w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim-150x150.jpg 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim-768x768.jpg 768w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim-1536x1536.jpg 1536w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Mei-Ling-Lim-2048x2048.jpg 2048w\" sizes=\"(max-width: 2140px) 100vw, 2140px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-654b9fd elementor-widget elementor-widget-text-editor\" data-id=\"654b9fd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-556e998 e-con-full e-flex e-con e-child\" data-id=\"556e998\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32b1569 elementor-widget elementor-widget-heading\" data-id=\"32b1569\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">From Molecule to Manufacturing: Accelerating Biologics Development<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-83dc64c elementor-widget elementor-widget-text-editor\" data-id=\"83dc64c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Mei Ling Lim<br \/><\/strong>PhD, MBA, Director Global Business Development<br \/>Sanyou Bio<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d4db9f elementor-widget elementor-widget-text-editor\" data-id=\"1d4db9f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Sanyou Bio is a global biopharmaceutical R&amp;D partner providing integrated solutions to support the development of innovative biologics from early-stage molecules through preclinical development and process optimization. Our capabilities span molecule generation and engineering, developability assessment, cell line development, upstream and downstream process development, analytical characterization, formulation, and scale-up.<\/p><p>By integrating advanced technology platforms with comprehensive wet-lab and bioprocessing capabilities, Sanyou supports the development of diverse biologic modalities, including monoclonal and multispecific antibodies, single-domain antibodies, ADCs, fusion proteins, and other next-generation biologics.<\/p><p>With experience across\u00a01,200+ projects, 2,000+ collaborative clients, 170+ patents, and 10+ CPO projects approved for IND, Sanyou provides flexible R&amp;D solutions for biotechnology and pharmaceutical partners, helping advance promising biologic candidates toward\u00a0robust, scalable development and manufacturing readiness.<\/p><p><em><strong>Mei Ling Lim<\/strong> is Director of Global Business Development at Sanyou Bio, where she works with biotechnology and pharmaceutical companies worldwide to establish and develop strategic R&amp;D collaborations. She focuses on connecting partners with Sanyou Bio\u2019s integrated capabilities across antibody and molecule discovery, biologics development, and preclinical R&amp;D, supporting innovative drug programs from early discovery toward IND. Her role centers on understanding partners\u2019 R&amp;D needs and identifying suitable external solutions and collaboration models to help advance the translation and development of innovative biologics.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-55f5ef9 e-flex e-con-boxed e-con e-parent\" data-id=\"55f5ef9\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9a53099 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"9a53099\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a7c2dbd e-flex e-con-boxed e-con e-parent\" data-id=\"a7c2dbd\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ca52491 elementor-widget elementor-widget-menu-anchor\" data-id=\"ca52491\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"AndersErnblad_ErikHoeglund\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-16d3e02 e-flex e-con-boxed e-con e-parent\" data-id=\"16d3e02\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b67638e e-con-full e-flex e-con e-child\" data-id=\"b67638e\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-acda407 e-flex e-con-boxed e-con e-child\" data-id=\"acda407\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-62dba22 elementor-widget elementor-widget-image\" data-id=\"62dba22\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1130\" height=\"1130\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Anders-Ernblad_Erik-Hoglund.png\" class=\"attachment-full size-full wp-image-2188\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Anders-Ernblad_Erik-Hoglund.png 1130w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Anders-Ernblad_Erik-Hoglund-300x300.png 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Anders-Ernblad_Erik-Hoglund-1024x1024.png 1024w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Anders-Ernblad_Erik-Hoglund-150x150.png 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Anders-Ernblad_Erik-Hoglund-768x768.png 768w\" sizes=\"(max-width: 1130px) 100vw, 1130px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6bbb7cc elementor-widget elementor-widget-text-editor\" data-id=\"6bbb7cc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-17ab0f8 e-con-full e-flex e-con e-child\" data-id=\"17ab0f8\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-478f2a2 elementor-widget elementor-widget-heading\" data-id=\"478f2a2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">From Idea to Manufacturing: A Modular Path to Your First Facility<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eb72494 elementor-widget elementor-widget-text-editor\" data-id=\"eb72494\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Anders Ernblad<br \/><\/strong>Front-End Design Manager<br \/>KeyPlants<\/p><p><strong>Erik H\u00f6glund<br \/><\/strong>Business Area and Sales Manager<br \/>KeyPlants<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a0682a elementor-widget elementor-widget-text-editor\" data-id=\"8a0682a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>For many emerging biotech companies, establishing in-house manufacturing can feel out of reach. The vision may be clear, but the cost, complexity and risk of building a pharmaceutical facility can quickly become a major barrier.<\/p><p>But what if you did not have to build the facility you may need five or ten years from now?<\/p><p>This presentation explores how biotech and advanced therapy companies can start with a small, fit-for-purpose production unit and expand it step by step as demand, funding and the business grow. By combining compact production pods with modular facility solutions, capacity can be added over time without requiring the full investment upfront.<\/p><p>The key is to build what you need today, while designing for tomorrow.<\/p><p>The session will show how a phased modular approach can lower the initial investment threshold, reduce project and financial risk, and make owning your manufacturing capability more achievable than you might think.<\/p><p><em><strong>Anders Ernblad<\/strong> has more than twenty-five years of experience in engineering projects, especially for the Life Science industry. He has a deep knowledge of the challenges in designing, engineering and building GxP-regulated facilities for different purposes and technologies having taken on roles as Project Manager and Director, Design and Engineering Manager and various SME roles in small and large life science projects for clients ranging from small start-ups to major global players in the industry. <\/em><em>He is also the chairman for the CoP (Community of Practice) for Project Management in the Nordic affiliate of ISPE<strong>.<\/strong> He holds a master&#8217;s degree in chemical engineering from the Engineering Faculty at Lund University.\u00a0<\/em><\/p><p><em><strong>Erik H\u00f6glund<\/strong> has been Engineering and business leader with 20+ years of experience leading technical organizations, multidisciplinary teams, and complex industrial operations in project-intensive and regulated environments. Strong track record of building organizations, driving transformation, and delivering large investment and operational improvement projects across engineering, Life Science, quality, production, and supply chain. Known for combining strategic leadership with hands-on execution, creating structure in complex environments, and building engaged, high-performing teams through trust, clarity, and accountability.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-352bc84 e-flex e-con-boxed e-con e-parent\" data-id=\"352bc84\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9e28d21 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"9e28d21\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f89517 e-flex e-con-boxed e-con e-parent\" data-id=\"6f89517\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3e06731 elementor-widget elementor-widget-menu-anchor\" data-id=\"3e06731\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"DavidBrunn\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0b43955 e-flex e-con-boxed e-con e-parent\" data-id=\"0b43955\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-cb3305f e-con-full e-flex e-con e-child\" data-id=\"cb3305f\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-aad2f20 e-flex e-con-boxed e-con e-child\" data-id=\"aad2f20\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dde6ff1 elementor-widget elementor-widget-image\" data-id=\"dde6ff1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2879\" height=\"2879\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099.jpg\" class=\"attachment-full size-full wp-image-2211\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099.jpg 2879w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099-300x300.jpg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099-1024x1024.jpg 1024w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099-150x150.jpg 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099-768x768.jpg 768w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099-1536x1536.jpg 1536w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/David-Brunn_1-215A3099-2048x2048.jpg 2048w\" sizes=\"(max-width: 2879px) 100vw, 2879px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-63781cc elementor-widget elementor-widget-text-editor\" data-id=\"63781cc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-358cc81 e-con-full e-flex e-con e-child\" data-id=\"358cc81\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b102661 elementor-widget elementor-widget-heading\" data-id=\"b102661\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Planning EU Market Entry? How Outsourced QP Release Accelerates Your Time to Market<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8e2241a elementor-widget elementor-widget-text-editor\" data-id=\"8e2241a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>David Brunn<br \/><\/strong>Qualified Person &amp; Project Manager Biotech<br \/>Midas Pharma<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f86ffe5 elementor-widget elementor-widget-text-editor\" data-id=\"f86ffe5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"Normal1\"><span lang=\"EN-GB\">For biotech start-ups, the leap from promising early-stage data to a clinical trial in Europe is one of the most critical and often underestimated steps in a product&#8217;s journey. For lean teams without in-house quality infrastructure and experienced staff, this can feel like an overwhelming hurdle with unforeseeable costs.<\/span><\/p><p class=\"Normal1\"><span lang=\"EN-GB\">This presentation shows how outsourced QP Release and an established EU Batch Release Site can bridge critical gaps in quality oversight, regulatory readiness and batch certification. We will discuss practical scenarios for non-EU suppliers and CDMO-based supply models, including common pitfalls and how early QP involvement can support faster, more credible EU access strategies.<\/span><\/p><p><em><strong>David Brunn<\/strong> is Qualified Person at Midas Pharma GmbH with a wealth of experience in the pharmaceutical and biotechnology industry. He holds a degree in pharmacy and a PhD in cancer immunology. Throughout his career, David has supported start-ups and established companies in analytical developing clinical trial material, in managing batch certification activities and processes, and in navigating the EU regulatory requirements. This includes ATMPs, antibodies and small molecules.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c3f2cac e-flex e-con-boxed e-con e-parent\" data-id=\"c3f2cac\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fa9d764 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"fa9d764\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-537cd6e e-flex e-con-boxed e-con e-parent\" data-id=\"537cd6e\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-73eacb0 elementor-widget elementor-widget-menu-anchor\" data-id=\"73eacb0\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"ThomasKofoed\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-82f7a2f e-flex e-con-boxed e-con e-parent\" data-id=\"82f7a2f\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-86c65c0 e-con-full e-flex e-con e-child\" data-id=\"86c65c0\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-76d282b e-flex e-con-boxed e-con e-child\" data-id=\"76d282b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d58a50e elementor-widget elementor-widget-image\" data-id=\"d58a50e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"939\" height=\"939\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Thomas-Kofoed.jpg\" class=\"attachment-full size-full wp-image-2221\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Thomas-Kofoed.jpg 939w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Thomas-Kofoed-300x300.jpg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Thomas-Kofoed-150x150.jpg 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Thomas-Kofoed-768x768.jpg 768w\" sizes=\"(max-width: 939px) 100vw, 939px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d80548 elementor-widget elementor-widget-text-editor\" data-id=\"3d80548\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-77ebeeb e-con-full e-flex e-con e-child\" data-id=\"77ebeeb\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-04fd873 elementor-widget elementor-widget-heading\" data-id=\"04fd873\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">LC-MS for Host Cell Protein Control: Insights on Changing Regulatory Expectations<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-29184ab elementor-widget elementor-widget-text-editor\" data-id=\"29184ab\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Thomas Kofoed<br \/><\/strong>CEO<br \/>Alphalyse<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-45d8dfc elementor-widget elementor-widget-text-editor\" data-id=\"45d8dfc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Host cell proteins (HCPs) are among the most scrutinized impurities in biologics manufacturing. For decades, enzyme-linked immunosorbent assay (ELISA) has been the industry workhorse for measuring total HCP content. But ELISA has a structural blind spot: its antibodies detect only the limited set of HCPs they were raised against, and it cannot reveal which individual proteins are actually present in a sample. As a result, regulatory authorities increasingly request liquid chromatography-mass spectrometry (LC-MS)-based HCP characterization to identify and quantify individual HCPs and support data-driven risk assessment. Drawing on client case examples, this presentation shows how LC-MS analysis complements and strengthens ELISA-based testing, and outlines what a combined, regulator-ready HCP control strategy looks like in practice.<\/p><p><em><strong>Thomas Kofoed<\/strong>, PhD, is CEO of Alphalyse A\/S, the world&#8217;s leading provider of LC-MS-based analysis of host cell proteins and other residual protein impurities in biopharmaceutical products. Since co-founding Alphalyse in 2002, Thomas has been at the forefront of advancing LC-MS applications for HCP analysis across the biopharmaceutical product lifecycle, from early-stage development to GMP release testing. A recognized thought leader in the field, he is a frequent speaker at international conferences and webinars, where he shares practical insights on HCP control strategies, regulatory expectations, GMP-compliant analysis, process understanding, and the role of LC-MS as both an orthogonal method and a powerful complement or alternative to ELISA.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-01f7a3f e-flex e-con-boxed e-con e-parent\" data-id=\"01f7a3f\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-073e41e elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"073e41e\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dc58c3a e-flex e-con-boxed e-con e-parent\" data-id=\"dc58c3a\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-94b92d0 elementor-widget elementor-widget-menu-anchor\" data-id=\"94b92d0\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"KristinaKarale\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-af80412 e-flex e-con-boxed e-con e-parent\" data-id=\"af80412\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2223b3c e-con-full e-flex e-con e-child\" data-id=\"2223b3c\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-4bd9da9 e-flex e-con-boxed e-con e-child\" data-id=\"4bd9da9\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-02f18d6 elementor-widget elementor-widget-image\" data-id=\"02f18d6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"3024\" height=\"3024\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale.jpeg\" class=\"attachment-full size-full wp-image-2231\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale.jpeg 3024w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale-300x300.jpeg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale-1024x1024.jpeg 1024w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale-150x150.jpeg 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale-768x768.jpeg 768w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale-1536x1536.jpeg 1536w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/08\/Kristina-Karale-2048x2048.jpeg 2048w\" sizes=\"(max-width: 3024px) 100vw, 3024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-63e82e5 elementor-widget elementor-widget-text-editor\" data-id=\"63e82e5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a97cba4 e-con-full e-flex e-con e-child\" data-id=\"a97cba4\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8fd8026 elementor-widget elementor-widget-heading\" data-id=\"8fd8026\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Beyond Standard Oligonucleotides: Expanding the Therapeutic Toolbox Through Custom Chemistry<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a09ccfa elementor-widget elementor-widget-text-editor\" data-id=\"a09ccfa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Kristina Karal\u0117<br \/><\/strong>Senior Scientist<br \/>RISE (Research Institutes of Sweden)<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da8eb99 elementor-widget elementor-widget-text-editor\" data-id=\"da8eb99\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Advances in oligonucleotide therapeutics are creating a need for more advanced chemical solutions than those offered by standard synthesis platforms. Emerging therapeutic concepts increasingly rely on custom nucleoside modifications, advanced linker technologies, and selective conjugation strategies to improve delivery, activity, and specificity.<br \/>This presentation will explore how tailored building blocks and enabling chemistries can expand the accessible chemical space of oligonucleotide therapeutics. Drawing on experience in the development of modified nucleotides, non-standard monomers, and oligonucleotide conjugates, the talk will highlight key challenges in synthesis, process development, and analytical characterization. Through selected examples, it will illustrate how strategic molecular design and custom chemistry can support the development of next-generation oligonucleotide therapeutics and conjugate-based modalities.<\/p><p><em><strong>Kristina Karal\u0117<\/strong> is a Senior Scientist at RISE working in the field of oligonucleotide therapeutics. She obtained her PhD in Medicinal Sciences from Karolinska Institutet through a joint project with RISE focused on oligonucleotide chemistry. Her research interests include modified nucleotides, custom building blocks, oligonucleotide conjugates, and the use of chemistry to enable novel therapeutic modalities. At RISE, she works in multidisciplinary projects together with academic and industrial partners, supporting the development and characterization of advanced biomolecular constructs.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a3a760b e-flex e-con-boxed e-con e-parent\" data-id=\"a3a760b\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-52fcae5 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"52fcae5\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-730fd80 e-flex e-con-boxed e-con e-parent\" data-id=\"730fd80\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bce63a2 elementor-widget elementor-widget-menu-anchor\" data-id=\"bce63a2\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"KnutSteffensen\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f9f438b e-flex e-con-boxed e-con e-parent\" data-id=\"f9f438b\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-497c4e5 e-con-full e-flex e-con e-child\" data-id=\"497c4e5\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-8b087d0 e-flex e-con-boxed e-con e-child\" data-id=\"8b087d0\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2b313fe elementor-widget elementor-widget-image\" data-id=\"2b313fe\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"640\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Knut-Steffensen.jpg\" class=\"attachment-full size-full wp-image-2258\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Knut-Steffensen.jpg 640w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Knut-Steffensen-300x300.jpg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Knut-Steffensen-150x150.jpg 150w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22f7ab3 elementor-widget elementor-widget-text-editor\" data-id=\"22f7ab3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fea3b7a e-con-full e-flex e-con e-child\" data-id=\"fea3b7a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3e59682 elementor-widget elementor-widget-heading\" data-id=\"3e59682\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">University Hospitals and Universities Are Emerging Innovation Ecosystems in ATMP Development<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ef2bf83 elementor-widget elementor-widget-text-editor\" data-id=\"ef2bf83\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Knut Steffensen<br \/><\/strong>Director<br \/>Karolinska ATMP Center<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ba62c4c elementor-widget elementor-widget-text-editor\" data-id=\"ba62c4c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span data-olk-copy-source=\"MessageBody\">The potential of ATMPs to relieve and cure severe diseases has led to large investments in developing new advanced treatments. Leading universities and hospitals have evolved from traditional centres of care, education, research and sporadic innovation into fully recognised Hubs for thriving innovation ecosystems. Both research and clinical trials using ATMPs are expanding in the academic setting, and the combined role of universities and university hospitals have a unique position to develop life saving new ATMP treatments with its own ecosystem. However, collaboration and partnership within the larger ATMP ecosystem is necessary to succeed in bringing the research and therapies to patients. Karolinska ATMP Center builds on the collective strengths of Karolinska University Hospital and Karolinska Institutet to accelerate in house translational research into clinical applications while interacting with the &#8220;glocal&#8221; ATMP ecosystem with academia and industry to strengthen its competitiveness.<\/span><\/p><div data-olk-copy-source=\"MessageBody\"><em><strong>Knut Steffensen<\/strong> is Director of the Karolinska ATMP Center, a strategic collaboration between Karolinska Institutet and Karolinska University Hospital advancing cell, gene, and tissue therapies from bench to bedside.<\/em><\/div><div><em>He brings a rare dual perspective to the field: 20 years in academia at Karolinska Institutet, where he became docent in molecular medicine and led his own research group, paired with eight years in the pharmaceutical industry launching new therapies into the Nordic health care system. A role as Nordic Medical Lead in Cell Therapy where he helped bring CAR T-cell therapy into clinical use has led to a deep understanding of the complexity of introducing new advanced therapies in the Nordics.<\/em><\/div><div><em>At the Karolinska ATMP Center, Steffensen is driving closer collaboration between research, healthcare, industry, and policy to accelerate the delivery of advanced therapies to patients. Under his leadership, the center has expanded its local and global collaboration on cell and gene therapies, including a strategic partnership with academic and industry aimed at pooling expertise to bring pioneering treatments to more patients.<\/em><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-12445ac e-flex e-con-boxed e-con e-parent\" data-id=\"12445ac\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-456f613 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"456f613\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8305afa e-flex e-con-boxed e-con e-parent\" data-id=\"8305afa\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-19e3fe3 elementor-widget elementor-widget-menu-anchor\" data-id=\"19e3fe3\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"JamesHumphrey\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b399b72 e-flex e-con-boxed e-con e-parent\" data-id=\"b399b72\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-e93df96 e-con-full e-flex e-con e-child\" data-id=\"e93df96\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-90dae51 e-flex e-con-boxed e-con e-child\" data-id=\"90dae51\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cc1392d elementor-widget elementor-widget-text-editor\" data-id=\"cc1392d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-49ef316 e-con-full e-flex e-con e-child\" data-id=\"49ef316\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e8e2109 elementor-widget elementor-widget-heading\" data-id=\"e8e2109\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The Critical Role of Bioprocessing Surfactants in Upstream and Downstream Biotherapeutic Manufacture<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c21eb0d elementor-widget elementor-widget-text-editor\" data-id=\"c21eb0d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>James Humphrey<br \/><\/strong>Research &amp; Technology Specialist<br \/>Croda Pharma<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a3fcebb elementor-widget elementor-widget-text-editor\" data-id=\"a3fcebb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span data-olk-copy-source=\"MessageBody\">Bioprocessing aids such as surfactants play a key role in maximising the output of production cell lines, alongside their importance in producing and maintaining a safe, efficacious, and high purity drug substance throughout the downstream process. In this talk we shall discuss how Croda Pharma has developed and optimised specific surfactants for upstream processing to insure consistency in performance and quality. In downstream we will demonstrate how surfactants can be used for processes such as viral inactivation, cell lysis, antibody stability and purification.<\/span><\/p><p><em><strong>James Humphrey<\/strong> is a chemist by training and has nearly 20 years\u2019 experience in the raw materials for pharmaceutical sector. Working at Croda he has focused on utilising Croda Pharma\u2019s range of excipients and bioprocessing aids for pharmaceutical formulations and processes. Over the last decade James has led the development of new materials and applications areas for the biopharmaceutical sector, with particular interest on the role of surfactants in cell growth, lysis, downstream processing and how best to stabilise and protect the drug substance in the final formulation.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2dd3937 e-flex e-con-boxed e-con e-parent\" data-id=\"2dd3937\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4cc112 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"f4cc112\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3e6ebf7 e-flex e-con-boxed e-con e-parent\" data-id=\"3e6ebf7\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-280537f elementor-widget elementor-widget-menu-anchor\" data-id=\"280537f\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"MinWenKu\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3187eb1 e-flex e-con-boxed e-con e-parent\" data-id=\"3187eb1\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-33ab35c e-con-full e-flex e-con e-child\" data-id=\"33ab35c\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-5216f26 e-flex e-con-boxed e-con e-child\" data-id=\"5216f26\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-146ad01 elementor-widget elementor-widget-image\" data-id=\"146ad01\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"640\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Min-Wen-ku.jpeg\" class=\"attachment-full size-full wp-image-2263\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Min-Wen-ku.jpeg 640w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Min-Wen-ku-300x300.jpeg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2026\/09\/Min-Wen-ku-150x150.jpeg 150w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f9bea7f elementor-widget elementor-widget-text-editor\" data-id=\"f9bea7f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b792c5b e-con-full e-flex e-con e-child\" data-id=\"b792c5b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bc0f5d3 elementor-widget elementor-widget-heading\" data-id=\"bc0f5d3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Starting Upstream: Plasmid Innovations for Better AAV Manufacturing<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c182b60 elementor-widget elementor-widget-text-editor\" data-id=\"c182b60\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Min Wen Ku<br \/><\/strong><span data-olk-copy-source=\"MessageBody\">Commercial Strategy<\/span><br \/>VectorBuilder<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6dd7b63 elementor-widget elementor-widget-text-editor\" data-id=\"6dd7b63\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span data-olk-copy-source=\"MessageBody\">Adeno-associated virus (AAV) is widely used in cell and gene therapy, yet clinical translation remains challenging, with approximately 90% of trials failing, largely due to suboptimal vector design that compromises efficacy, safety, and manufacturability. Here, we highlight the power of a rational vector design approach, where all components of the transfer vector are carefully considered to facilitate a seamless transition from early research stages to the clinic. Firstly, we optimized the transfer vector backbone by stabilizing the mutation-prone inverted terminal repeats (ITRs), which are crucial for consistent, high-titer manufacturing. This reduced the ITR mutation rate after 10 serial passages in E. coli from 31.8-48.1% down to 0%. Next, promoter optimization markedly enhanced efficacy, as evidenced by increased survival in transgenic knockout mice treated with an AAV-based gene-replacement therapy. Finally, through ORF optimization, we generated truncated ORFs that further enhanced therapeutic efficacy. Overall, these findings highlight the importance of optimized vector design for consistent, high-titer AAV production and accelerated clinical translation.<\/span><\/p><p><em><strong>Min Wen Ku<\/strong> is a Commercial Strategist at VectorBuilder, where she works with academic, biotechnology, and pharmaceutical organizations to establish and develop gene delivery collaborations. She focuses on connecting partners across different delivery modalities, including AAV, LV and mRNA-LNP, and supports gene therapy programs from early discovery toward IND. Her role centers on understanding partners&#8217; scientific needs and advising them on suitable delivery modalities to help advance the translation and development of genetic medicines.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-57c92b0 e-flex e-con-boxed e-con e-parent\" data-id=\"57c92b0\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-abe11c0 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"abe11c0\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-438d8cf elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"438d8cf\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5de3f69 elementor-widget elementor-widget-heading\" data-id=\"5de3f69\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">2025:<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-238a43c elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"238a43c\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-92bf9f3 e-con-full e-flex e-con e-child\" data-id=\"92bf9f3\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-c6534ae e-flex e-con-boxed e-con e-child\" data-id=\"c6534ae\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a4fce9e elementor-widget elementor-widget-image\" data-id=\"a4fce9e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Veronique-Chotteau-rd8ffizgz7xvxfsv0w1frdvtr918yip6uhg6vzfrm0.jpg\" title=\"Veronique Chotteau\" alt=\"Veronique Chotteau\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a8790b9 elementor-widget elementor-widget-text-editor\" data-id=\"a8790b9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da7c8da elementor-widget elementor-widget-text-editor\" data-id=\"da7c8da\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-87af1de e-con-full e-flex e-con e-child\" data-id=\"87af1de\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bda175c elementor-widget elementor-widget-heading\" data-id=\"bda175c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Enabling and Intensifying Manufacturing of Biologics<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f2eb2e elementor-widget elementor-widget-text-editor\" data-id=\"4f2eb2e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>V\u00e9ronique Chotteau<br \/><\/b>Professor in\u00a0Mammalian Cell-Based Bioprocess\u00a0Technology<br \/>KTH Royal Institute of Technology<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-66883b2 elementor-widget elementor-widget-text-editor\" data-id=\"66883b2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><em>Professor V\u00e9ronique Chotteau, Director of AdBIOPRO Competence Centre for Advanced Bioproduction by Continuous Processing, is the Leader of the Cell Technology group, Dept. Industrial Biotechnology, at KTH (Royal Institute of Technology), Stockholm. She has a background of MSc Electrical Engineering, MSc Biotechnology, PhD Automatic Control\/Modelling\/Biotechnology (University of Louvain, Belgium), and has built her career in the biopharmaceutical area. Chotteau has more than 30 years of experience in mammalian cell culture including \u2265 10 years in biopharmaceutical industry (at Pharmacia Upjohn\/Biovitrum, Stockholm, nowadays Swedish Orphan Biovitrum). She joined KTH in 2008, when she was offered to lead the animal cell cultivation activities. Her group is focusing on cell-based processes for biologics production and intensification by continuous processing, mathematical modelling, process analytical technology including biomanufacturing for gene therapy and cell therapy. She was the first to publish cell densities higher than 200 millions cells\/mL in CHO cell perfusion process.<\/em><br \/><em>AdBIOPRO, The Competence Centre for Advanced BioProduction, provides a dynamic hub for world-leading knowledge and technology development for manufacturing therapeutic antibodies, glycoproteins, and cell and gene therapy products. AdBIOPRO is driven by the multi-disciplinary expertise of seven teams at KTH, Lund University, the Karolinska Cell Therapy Centre (KCC) at Karolinska University Hospital, Karolinska Institutet and Link\u00f6ping University together with sixteen industrial partners.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1b8cf74 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"1b8cf74\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d91d915 e-con-full e-flex e-con e-child\" data-id=\"d91d915\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-2f710bd e-flex e-con-boxed e-con e-child\" data-id=\"2f710bd\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-03f645e elementor-widget elementor-widget-image\" data-id=\"03f645e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Ulf-Stahl-scaled-rd8ffizgz7xvxfsv0w1frdvtr918yip6uhg6vzfrm0.jpeg\" title=\"Ulf St\u00e5hl\" alt=\"Ulf St\u00e5hl\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4dffe4c elementor-widget elementor-widget-text-editor\" data-id=\"4dffe4c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a1bb6dd elementor-widget elementor-widget-text-editor\" data-id=\"a1bb6dd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e2ebc01 e-con-full e-flex e-con e-child\" data-id=\"e2ebc01\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-46ebb40 elementor-widget elementor-widget-heading\" data-id=\"46ebb40\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">In-House Development of a Protein-Based Biological Drug: A Next-Generation Botulinum Neuromodulator Product for the Aesthetic Market<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-befed63 elementor-widget elementor-widget-text-editor\" data-id=\"befed63\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Ulf St\u00e5hl<br \/><\/b>PhD, Product Research Leader<br \/>Galderma<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d414ca5 elementor-widget elementor-widget-text-editor\" data-id=\"d414ca5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>For more than 15 years, Galderma Uppsala has developed a fully in-house, next-generation botulinum neurotoxin product for the aesthetic market, which has since been launched and approved in several European countries and in Australia. Botulinum neurotoxin is a highly active and delicate protein molecule produced by the bacterium <em>Clostridium botulinum<\/em>. It has been used for many years in both therapeutic and aesthetic indications. Galderma\u2019s new product is a complex-free neurotoxin, presented as a ready-to-use liquid formulation. The manufacturing process, developed by Galderma, is termed PEARL\u2122 Technology. This process employs modern protein separation techniques in combination with single-use systems. The toxin is preserved in its natural conformation in liquid state throughout processing, thereby ensuring the high specific potency of the product.<\/p><p><em>Ulf has a PhD in plant lipid biochemistry focusing on protein purification from the Swedish University of Agriculture Sciences (SLU) followed by 10 years of research in the field of lipid biosynthesis in eucaryotic cells with about ten peer reviewed scientific publications. From 2008 Ulf has worked with process development for an aesthetic biological product within Q-Med AB \/ Galderma. Initially working for two years as protein purification specialist in the early discovery phase of the project and then as team leader for the Bioprocess Development team, following the project development through all project phases such as toxicology, clinical, process validation and launch of the new innovative liquid toxin product.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-38fde7f elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"38fde7f\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c35ef80 e-con-full e-flex e-con e-child\" data-id=\"c35ef80\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-c1fdb47 e-flex e-con-boxed e-con e-child\" data-id=\"c1fdb47\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b654756 elementor-widget elementor-widget-image\" data-id=\"b654756\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Ewa-Ellis-rezbpzmb5d3ep9hwtgq8kztnd0mk7ogp1m1s8j4rrc.jpg\" title=\"Ewa Ellis\" alt=\"Ewa Ellis\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da86235 elementor-widget elementor-widget-text-editor\" data-id=\"da86235\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0bb69ec elementor-widget elementor-widget-text-editor\" data-id=\"0bb69ec\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f6bfe24 e-con-full e-flex e-con e-child\" data-id=\"f6bfe24\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2b59f9a elementor-widget elementor-widget-heading\" data-id=\"2b59f9a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Karolinska ATMP Center: Accelerating Translational Research into Clinical Application<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eac3406 elementor-widget elementor-widget-text-editor\" data-id=\"eac3406\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Ewa C S Ellis<br \/><\/b>ATMP Coordinator, Karolinska ATMP Center<br \/>Karolinska Institutet<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b3fb29 elementor-widget elementor-widget-text-editor\" data-id=\"8b3fb29\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Karolinska ATMP Center builds\u00a0on the collective strength of both Karolinska Institutet and Karolinska University Hospital to drive academic research into clinical application and patient care. The center further aims to collaborate across the Swedish ATMP ecosystem both serving as a national infrastructure for ATMP manufacturing and a partner for both industry and academic institutions.<\/p><p><em>Assistant professor Ewa Ellis has a long experience as a researcher in experimental medicine, she is docent in experimental gastroenterology and hepatology. Dr. Ellis has vast expertise in isolation of human liver cells and liver perfusion and is a certified organ perfusionist.<\/em><\/p><p><em>As the ATMP coordinator at Karolinska ATMP Center and Karolinska Center for Cell Therapy Dr. Ellis manages the priority board and the single-entry-point for ATMP and Cell transplantation at Karolinska. She has been a core-team member of the national Innovation milieu \u201cSweden leader in ATMP year 2030\u201d.<\/em><\/p><p><em>Dr. Ellis has hands-on experience as head of the production of primary liver cells for clinical transplantation within a tissue facility with permission from the Health and Social Care Inspectorate (IVO).<\/em><br \/><em>She has been a board member in several professional organizations in cell therapy, regenerative medicine, transplantation and liver research and has participated in the organization of several local, national and international congresses within the framework of these.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-222b42e elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"222b42e\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5106a96 e-con-full e-flex e-con e-child\" data-id=\"5106a96\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-c5932b6 e-flex e-con-boxed e-con e-child\" data-id=\"c5932b6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-86330e2 elementor-widget elementor-widget-image\" data-id=\"86330e2\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Asa-Derolf-rd8ffi1msdwlltu86dmt6w4d5v5vqtlgicspeph5s8.jpg\" title=\"\u00c5sa Derolf\" alt=\"\u00c5sa Derolf\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-53bbb42 elementor-widget elementor-widget-text-editor\" data-id=\"53bbb42\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26eae5e elementor-widget elementor-widget-text-editor\" data-id=\"26eae5e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b21beb8 e-con-full e-flex e-con e-child\" data-id=\"b21beb8\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-51bb838 elementor-widget elementor-widget-heading\" data-id=\"51bb838\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Introducing Cell and Gene Therapies in Sweden \u2013 the Role of the New Therapies Council<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-98ad5ef elementor-widget elementor-widget-text-editor\" data-id=\"98ad5ef\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>\u00c5sa Derolf<br \/><\/strong>Chair<br \/>the New Therapies Council<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1d0a6f elementor-widget elementor-widget-text-editor\" data-id=\"b1d0a6f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>In order to achieve an equal, cost-effective and appropriate use of new pharmaceutical drugs for all patients in Sweden, all regions, several governmental agencies and the pharmaceutical industry collaborate in a joint process for the introduction of new therapies. The New Therapies Council has the regions&#8217; mandate to issue recommendations on the use of new therapies that are subject to national joint introduction. In recent years there has been a great development in the field of cell- and gene therapies and several of theses therapies have been introduced in Sweden through this joint national process.<\/p><p><em>\u00c5sa Rangert Derolf is a specialist in hematology and PhD and has been head of the Department of Hematology at the Karolinska University Hospital. As a hematologist and researcher she has had an interest in acute leukemias and precision medicine. She I currently the head of the Swedish New Therapies council.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ff6c7f1 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"ff6c7f1\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-93727d0 e-con-full e-flex e-con e-child\" data-id=\"93727d0\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-925d99f e-flex e-con-boxed e-con e-child\" data-id=\"925d99f\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ef919bd elementor-widget elementor-widget-image\" data-id=\"ef919bd\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Fredrik-Sjoo_fix-rd8ffizgz7xvxfsv0w1frdvtr918yip6uhg6vzfrm0.png\" title=\"Fredrik Sj\u00f6\u00f6_fix\" alt=\"Fredrik Sj\u00f6\u00f6_fix\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-12aca2d elementor-widget elementor-widget-text-editor\" data-id=\"12aca2d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f602541 elementor-widget elementor-widget-text-editor\" data-id=\"f602541\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6dc9ab1 e-con-full e-flex e-con e-child\" data-id=\"6dc9ab1\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0b3b452 elementor-widget elementor-widget-heading\" data-id=\"0b3b452\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The Price of Innovation: How Do We Ensure Access to Gene Therapy?<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d695f3 elementor-widget elementor-widget-heading\" data-id=\"7d695f3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">New payment models are needed for life-changing rare disease therapies<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b4f73fa elementor-widget elementor-widget-text-editor\" data-id=\"b4f73fa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Fredrik Sj\u00f6\u00f6<br \/><\/b>Head of Medical Affairs, Nordic Region<br \/>CSL Behring<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a1f9043 elementor-widget elementor-widget-text-editor\" data-id=\"a1f9043\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The New Therapies Council (NT-r\u00e5det) recently chose not to recommend a gene therapy for hemophilia B. The cost was deemed too high \u2013 and the council highlighted uncertainty regarding how long the treatment\u2019s effects would last.<\/p><p>Sweden is below the EU average when it comes to patient access to treatments for rare conditions. According to this year\u2019s WAIT survey, patients in 20 European countries have access to more orphan drugs than patients in Sweden.<\/p><p>This highlights the importance of developing new payment models for therapies targeting rare and severe diseases. Outcome-based agreements \u2013 where payment is linked to a treatment\u2019s clinical outcome \u2013 can help reduce the financial risk for payers in terms of projected spending, potential cost savings, and improved health outcomes.<\/p><p>Several countries have already implemented such agreements. Denmark, for instance, considers this payment model to be cost saving. During his presentation, Fredrik Sj\u00f6\u00f6, Head of Medical Affairs Nordic Region at CSL Behring, discusses how other European countries have approached this, why it is successful there, and how we can work together to ensure that new, innovative treatments benefit patients \u2013 also in Sweden.<\/p><p>If no one is willing to pay for gene therapies today, there will be no gene therapies tomorrow.<\/p><p><em>Fredrik Sj\u00f6\u00f6 is a seasoned medical affairs leader with a clinical background in hematology and extensive experience in the pharmaceutical industry. He currently serves as the Head of Medical Affairs for the Nordic Region at CSL Behring, based in Stockholm, Sweden, where he leads strategic medical initiatives and fosters collaboration across the Nordic markets. Fredrik earned both his MD and PhD from Karolinska Institutet. Before transitioning to industry, he spent many years as a clinical hematologist and section head at St G\u00f6rans Hospital in Stockholm. Fredrik is part of the Nordic launch team for Hemgenix, the first approved gene therapy for hemophilia B, contributing to its strategic planning and medical engagement across the region. His combined expertise in clinical medicine and pharmaceutical strategy positions him as a trusted partner to healthcare professionals and stakeholders.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-407e18d elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"407e18d\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3fd532c e-con-full e-flex e-con e-child\" data-id=\"3fd532c\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-4fd8326 e-flex e-con-boxed e-con e-child\" data-id=\"4fd8326\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cde7b77 elementor-widget elementor-widget-image\" data-id=\"cde7b77\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Anna-Lena-Spetz-rd8ffizgz7xvxfsv0w1frdvtr918yip6uhg6vzfrm0.jpg\" title=\"Anna-Lena Spetz\" alt=\"Anna-Lena Spetz\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c9e575 elementor-widget elementor-widget-text-editor\" data-id=\"2c9e575\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a60e628 elementor-widget elementor-widget-text-editor\" data-id=\"a60e628\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-032bb11 e-con-full e-flex e-con e-child\" data-id=\"032bb11\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1ee1077 elementor-widget elementor-widget-heading\" data-id=\"1ee1077\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Immune Checkpoint Induction by a Topical Oligonucleotide Therapy for Atopic Dermatitis<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-15ca141 elementor-widget elementor-widget-text-editor\" data-id=\"15ca141\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Anna-Lena Spetz<br \/><\/b>Chief Scientific Officer<br \/>TIRmed Pharma<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fdd7ffd elementor-widget elementor-widget-text-editor\" data-id=\"fdd7ffd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>TIRmed Pharma AB develops topical immunomodulatory therapies based on TIR-01, a single-stranded oligonucleotide functioning as a tolerogenic adjuvant. TIR-01 dampens TLR3-mediated inflammation, inhibits Th2\/9 and Th17 responses, and induces immune checkpoints (ILT3, PDL1) on myeloid cells, restoring immune balance in inflamed skin. Delivered via the TIR-C formulation for optimized uptake, this mechanism yields rapid reduction of atopic dermatitis symptoms and durable remission with minimal treatments. Proof-of-concept animal studies confirm high efficacy and safety, supporting broad dermatological potential.<\/p><p><em>Anna-Lena Spetz, MD, PhD, Professor, has thirty years of experience from research in immunology from academia, currently at the Stockholm University and has previous experiences from Karolinska Institutet, Institut Pasteur, and Dana-Farber Cancer Institute, Harvard Medical School. She has previous experiences from a small biotech as project leader and co-founder of Avaris AB (2001-2012) and is now founder and CSO of TIRmed Pharma AB.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f50d3d elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"6f50d3d\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ad1da52 e-con-full e-flex e-con e-child\" data-id=\"ad1da52\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-10a403a e-flex e-con-boxed e-con e-child\" data-id=\"10a403a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-48bc6fe elementor-widget elementor-widget-image\" data-id=\"48bc6fe\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Gunilla-Enblad-scaled-rd8ffi1msdwlltu86dmt6w4d5v5vqtlgicspeph5s8.jpg\" title=\"Gunilla Enblad\" alt=\"Gunilla Enblad\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-43e31a3 elementor-widget elementor-widget-text-editor\" data-id=\"43e31a3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-249f065 elementor-widget elementor-widget-text-editor\" data-id=\"249f065\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2867549 e-con-full e-flex e-con e-child\" data-id=\"2867549\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-504ddeb elementor-widget elementor-widget-heading\" data-id=\"504ddeb\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">CAR-T Cells \u2013 Swedish Experiences<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e5c9353 elementor-widget elementor-widget-text-editor\" data-id=\"e5c9353\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Gunilla Enblad<br \/><\/b>Professor in Oncology<br \/>Uppsala University<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e3b9c0a elementor-widget elementor-widget-text-editor\" data-id=\"e3b9c0a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>More info coming soon!<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ae62753 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"ae62753\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b7ec2c0 e-con-full e-flex e-con e-child\" data-id=\"b7ec2c0\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-08bf1e2 e-flex e-con-boxed e-con e-child\" data-id=\"08bf1e2\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e0f99ab elementor-widget elementor-widget-image\" data-id=\"e0f99ab\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Per-Ola-Carlsson_fotograf-Johan-Alp-rd8ffi1msdwlltu86dmt6w4d5v5vqtlgicspeph5s8.jpg\" title=\"Per-Ola Carlsson_fotograf Johan Alp\" alt=\"Per-Ola Carlsson_fotograf Johan Alp\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7565250 elementor-widget elementor-widget-text-editor\" data-id=\"7565250\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Photo: Johan Alp<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aabc1e8 elementor-widget elementor-widget-text-editor\" data-id=\"aabc1e8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fa47376 e-con-full e-flex e-con e-child\" data-id=\"fa47376\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-011976a elementor-widget elementor-widget-heading\" data-id=\"011976a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Transplantation of Allogeneic Beta Cells with No Immunosuppression<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9fe468c elementor-widget elementor-widget-text-editor\" data-id=\"9fe468c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Per-Ola Carlsson<br \/><\/strong>Professor of Medical Cell Biology<br \/>Uppsala University<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-27c6737 elementor-widget elementor-widget-text-editor\" data-id=\"27c6737\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>We have clinically translated the concept of immune evasion with hypoimmune (HIP) gene modifications entailing the depletion of HLA class I and II and overexpression of CD47 to enable allogeneic transplantation without immunosuppression. A patient with long-standing type 1 diabetes received allogeneic, gene modified, primary donor islet cells.\u00a0He did not mount any immune response against the HIP islet cells over a 26-week follow-up period. A PET-MRI at 12 weeks showed a GLP-1R signal at graft site. The patient developed stable C-peptide levels that increased in mixed meal tolerance tests.\u00a0This case confirms the immune evasive character of HIP cells in a patient and provides an optimistic outlook that immune evasion might be generalizable for more cell types, tissues and organs for allotransplantation without immunosuppression.<\/p><p><em>Per-Ola Carlsson is a professor of Medical Cell Biology at Uppsala University, Sweden. He also serves as a senior consultant in endocrinology and diabetology at Uppsala University Hospital and as director of Uppsala Diabetes Centre.<\/em><\/p><p><em>His research focus over the years has been on islet physiology, islet vascular biology, stem cell research, beta-cell replacement and early phase clinical cell therapy trials in type 1 diabetes. He has authored more than 200 peer-reviewed publications and is the P.I. of the presented first-in-human study of hypoimmune islet cell transplantation in type 1 diabetes.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8f6b149 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"8f6b149\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b597d20 e-con-full e-flex e-con e-child\" data-id=\"b597d20\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-053fc27 e-flex e-con-boxed e-con e-child\" data-id=\"053fc27\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6d5705b elementor-widget elementor-widget-image\" data-id=\"6d5705b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Alexandra-Patriksson-scaled-rdwolh7mt0nekm8ftvz1amyg313bxoazm3fx1u07m0.jpg\" title=\"Foto: Peter Holgersson AB\" alt=\"Foto: Peter Holgersson AB\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8d6f4eb elementor-widget elementor-widget-text-editor\" data-id=\"8d6f4eb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f1b1cb e-con-full e-flex e-con e-child\" data-id=\"6f1b1cb\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9a3920f elementor-widget elementor-widget-heading\" data-id=\"9a3920f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">BRIDGE Sweden \u2013 Accelerating Biologics Development through National Collaboration<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a86a8f elementor-widget elementor-widget-text-editor\" data-id=\"8a86a8f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Alexandra Patriksson<br \/><\/strong>Senior Manager<br \/>Testa Center<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b86641 elementor-widget elementor-widget-text-editor\" data-id=\"1b86641\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>BRIDGE Sweden is a national initiative supported by Vinnova and Swelife, aiming to accelerate the translation of academic innovations in biologics into industrial and clinical applications. By connecting infrastructures and expertise across Sweden, the project strengthens national capabilities in biologics development.<\/p><p>This presentation will introduce BRIDGE Sweden and its recently established cell line development service, designed to enable efficient screening, optimization, and production of biological pharmaceuticals. Klas Bratteby, representing the pilot project \u201cAdvancing Radiotheranostics for Solid Tumors\u201d within Thuy Tran\u2019s research group at Karolinska Institutet, will share insights on how this infrastructure enables the transition from academic discovery to scalable bioproduction, strengthening Sweden\u2019s position in life science innovation.<\/p><p><em>Alexandra has been working in the intersection of research and industry for the last 10 years, supporting academic researchers and start-ups with their innovation and industry collaboration projects. She has a PhD in Biophysics, a MSc in Molecular Biotechnology Engineering and master training from the school of entrepreneurship from Uppsala University.<\/em><\/p><p><em>She has several years of work experience in management consulting both at WM-data, Logica Sweden and in Deloitte Norway, and in public research and innovation funding and support in Innovation Norway, Oslo University and The Centre for Digital Life Norway, Uppsala University Innovation and SciLifeLab.<\/em><\/p><p><em>At Testa Center, Alexandra is working both with supporting clients as well as with internal business development, national research and innovation policy as well as ecosystem development. Being a creative and solution oriented person, Alexandra\u2019s ambition is to help the clients of Testa Center to develop their projects and ideas into products or services that can create value for society, by helping them understand how to access the existing innovation supporting organizations and funding opportunities.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e45f682 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"e45f682\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5fc8ad1 e-con-full e-flex e-con e-child\" data-id=\"5fc8ad1\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-8733b07 e-flex e-con-boxed e-con e-child\" data-id=\"8733b07\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2c1b51e elementor-widget elementor-widget-image\" data-id=\"2c1b51e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Niklas-Berndt-Thalen-rdwoqlg00jnls6sty3lwvcgsijv9ucmdnfb342f1qg.jpeg\" title=\"Niklas Berndt Thale\u0301n\" alt=\"Niklas Berndt Thale\u0301n\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6aa2958 elementor-widget elementor-widget-text-editor\" data-id=\"6aa2958\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b45cbfe e-con-full e-flex e-con e-child\" data-id=\"b45cbfe\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-857d26b elementor-widget elementor-widget-heading\" data-id=\"857d26b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">BRIDGE Sweden \u2013 Accelerating Biologics Development through National Collaboration<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-64d5e6a elementor-widget elementor-widget-text-editor\" data-id=\"64d5e6a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Niklas Berndt Thal\u00e9n<br \/><\/strong>Research Scientist<br \/>Drug Discovery and Development Platform, SciLifeLab Solna<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b61ffca elementor-widget elementor-widget-text-editor\" data-id=\"b61ffca\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>BRIDGE Sweden is a national initiative supported by Vinnova and Swelife, aiming to accelerate the translation of academic innovations in biologics into industrial and clinical applications. By connecting infrastructures and expertise across Sweden, the project strengthens national capabilities in biologics development.<\/p><p>This presentation will introduce BRIDGE Sweden and its recently established cell line development service, designed to enable efficient screening, optimization, and production of biological pharmaceuticals. Klas Bratteby, representing the pilot project \u201cAdvancing Radiotheranostics for Solid Tumors\u201d within Thuy Tran\u2019s research group at Karolinska Institutet, will share insights on how this infrastructure enables the transition from academic discovery to scalable bioproduction, strengthening Sweden\u2019s position in life science innovation.<\/p><p><em>PhD in Biotechnology with a Post-doc from the Royal Institute of Technology. Experienced in cellular engineering with a focus on enhancing the productivity of biological pharmaceuticals.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fbc94de elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"fbc94de\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c4d0ec4 e-con-full e-flex e-con e-child\" data-id=\"c4d0ec4\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-9164835 e-flex e-con-boxed e-con e-child\" data-id=\"9164835\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0f3014b elementor-widget elementor-widget-image\" data-id=\"0f3014b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Klas-Bratteby-scaled-rdxbahjh5x2nyxhe2jm41yuw2w5pemrw9wycv4m9ag.jpg\" title=\"Klas Bratteby\" alt=\"Klas Bratteby\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b690c65 elementor-widget elementor-widget-text-editor\" data-id=\"b690c65\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1f4cdf4 e-con-full e-flex e-con e-child\" data-id=\"1f4cdf4\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f1c9e4b elementor-widget elementor-widget-heading\" data-id=\"f1c9e4b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">BRIDGE Sweden \u2013 Accelerating Biologics Development through National Collaboration<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8877a8c elementor-widget elementor-widget-text-editor\" data-id=\"8877a8c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Klas Bratteby<br \/><\/strong>Research Specialist<br \/>Karolinska Institutet<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2dd5a8a elementor-widget elementor-widget-text-editor\" data-id=\"2dd5a8a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>BRIDGE Sweden is a national initiative supported by Vinnova and Swelife, aiming to accelerate the translation of academic innovations in biologics into industrial and clinical applications. By connecting infrastructures and expertise across Sweden, the project strengthens national capabilities in biologics development.<\/p><p>This presentation will introduce BRIDGE Sweden and its recently established cell line development service, designed to enable efficient screening, optimization, and production of biological pharmaceuticals. Klas Bratteby, representing the pilot project \u201cAdvancing Radiotheranostics for Solid Tumors\u201d within Thuy Tran\u2019s research group at Karolinska Institutet, will share insights on how this infrastructure enables the transition from academic discovery to scalable bioproduction, strengthening Sweden\u2019s position in life science innovation.<\/p><p><em>Klas received his Master of Science degree in Biotechnology from Lund University of Technology in 2017. He then completed research studies in Matthias Herth&#8217;s research group at the University of Copenhagen, where his work focused on radiolabeling with fluorine-18 of base-sensitive compounds and development of pretargeting strategies. After his doctoral dissertation in 2021, he worked at the cyclotron unit at Lund University Hospital, before joining Thuy Trans&#8217;s research group at Karolinska Institutet as a postdoctoral fellow in 2022.<\/em><\/p><p><em>In addition to his postdoctoral research, he is active as an R&amp;D radiochemist at Karolinska Hospital&#8217;s Theranostics Trial Center, where the focus is on translating preclinical projects to enable, among other things, First-in-human phase I studies in radiotheranostics. His current research focuses on the development of TROP-2-targeted theranostics drugs, with the goal of improving the precision of cancer diagnostics and treatment.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c57af70 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"c57af70\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b30cf7a e-con-full e-flex e-con e-child\" data-id=\"b30cf7a\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-240d00a e-flex e-con-boxed e-con e-child\" data-id=\"240d00a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c2280ca elementor-widget elementor-widget-image\" data-id=\"c2280ca\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Marko-Radukic-reljompit5pt5eb290u1bqjlrb9vo4zk7w5yxaezd4.jpg\" title=\"Marko Radukic\" alt=\"Marko Radukic\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b34b7ea elementor-widget elementor-widget-text-editor\" data-id=\"b34b7ea\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bf78739 e-con-full e-flex e-con e-child\" data-id=\"bf78739\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e0543dd elementor-widget elementor-widget-heading\" data-id=\"e0543dd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Navigating Adeno-Associated Virus Manufacturing Challenges through Analytical and Process Advances<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0aa533 elementor-widget elementor-widget-text-editor\" data-id=\"c0aa533\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Marco Radukic<br \/><\/strong>Research Scientist<br \/>Bielefeld University<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b4b5af elementor-widget elementor-widget-text-editor\" data-id=\"5b4b5af\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Adeno-associated virus (AAV) vectors remain the first choice for in vivo gene therapy, yet their unique molecular composition and typically low concentrations make them particularly challenging to manufacture and analyze. Shifting areas of analytical concern, such as capsid and genomic heterogeneity of the vector, demand new analytical workflows alongside process innovations to overcome these challenges and increase patient access. <br \/>The talk will introduce recent European guidelines concerning AAV quality, followed by our developments at Bielefeld University and Biofidus AG\/Midas aimed at meeting these new standards in a streamlined and cost-effective way. We demonstrate purpose-developed intact mass analysis for AAV capsid protein stoichiometry, as well as tandem mass spectrometry to investigate capsid identity and post-translational modifications from minimal sample input. In addition, next-generation sequencing reveals heterogeneities of the packaged DNA, including mispackaging and recombination, which may contribute to vector immunogenicity. Lastly, we highlight how some of these challenges could be addressed in the future by integrating our recent manufacturing advances early in the development process.<\/p><p><em>Marco Radukic has a doctorate in biotechnology and works as a research scientist at Bielefeld University, Germany. He is a consultant to Biofidus AG\/Midas Pharma GmbH. His contributions on improving the quality and manufacturability of adeno-associated virus vectors for gene therapy have won awards, including by the German Society of Cell and Gene Therapy. <\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d375d56 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"d375d56\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9992cff e-con-full e-flex e-con e-child\" data-id=\"9992cff\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-7607de7 e-flex e-con-boxed e-con e-child\" data-id=\"7607de7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f680083 elementor-widget elementor-widget-image\" data-id=\"f680083\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/elementor\/thumbs\/Heather-Main-rf9zqqbswe4gukae1a9x4db1t48eqnqb3qce4x1sp4.jpg\" title=\"Heather Main\" alt=\"Heather Main\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-467ad58 elementor-widget elementor-widget-text-editor\" data-id=\"467ad58\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8c03467 e-con-full e-flex e-con e-child\" data-id=\"8c03467\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-af09a4c elementor-widget elementor-widget-heading\" data-id=\"af09a4c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Engaging Ecosystems to Translate ATMPs From Bench to Bedside: Keeping an Eye on Commercialisation and Reimbursement<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-919ed16 elementor-widget elementor-widget-text-editor\" data-id=\"919ed16\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Heather Main<br \/><\/strong>Principle Consultant and Co-founder<br \/>HOYA Consulting<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-674730b elementor-widget elementor-widget-text-editor\" data-id=\"674730b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Based on a foundation of expert ecosystem engagement and activating &#8216;consider it early&#8217; points, we present some of the ways HOYA is addressing translational bottlenecks in ATMP. We will introduce (1) our efforts in streamlining access to commercially relevant GMP human pluripotent stem cell start material for cellular therapy, including direct interactions with the FDA and EMA and IP licensing organisations; (2) our evolving platform to make it easier for developers to match to the right raw materials, equipment, services and experts to create the best process and commercial business model for development; (3) our ambitions to Integrated Valuation Modelling to rescue investor interest in ATMP translation and finally; (4) our European consortium for synchronising modality specific ATMP competencies, for example in CMC, GMP manufacture, clinical trials design\/follow-up and education. Connecting the right competencies at the right moment, &#8216;with the end in mind&#8217;.\u00a0<\/p><p><em>Heather Main is co-founder of HOYA Consulting and acts as a strategic advisor and analyst in advanced therapies to accelerate ATMP translation towards scalable, commercially viable\u00a0products. Heather&#8217;s ATMP competency comes from initiating and running ATMP Sweden between 2018 and 2024, translating hPSC derived RPE to GMP manufacture at Vecura 2018-2022 and running an online forum of hPSC derived cell therapy developers since 2022. These experiences give Heather a unique network and ability to support translational projects through regulatory, quality, manufacturing and commercial decisions, derived from detailed ecosystem analysis. At HOYA, she leads multi-stakeholder initiatives that bridge academic innovation and industrial capability, supporting developers in building the right teams, reducing translational friction, and accelerating the path to real-world access.\u00a0<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-46670cc elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"46670cc\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ce48d27 e-con-full e-flex e-con e-child\" data-id=\"ce48d27\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-df66b2a e-flex e-con-boxed e-con e-child\" data-id=\"df66b2a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e431ade elementor-widget elementor-widget-image\" data-id=\"e431ade\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"304\" height=\"444\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Jan-Stalemark.png\" class=\"attachment-large size-large wp-image-1933\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Jan-Stalemark.png 304w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Jan-Stalemark-205x300.png 205w\" sizes=\"(max-width: 304px) 100vw, 304px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9e37ef4 elementor-widget elementor-widget-text-editor\" data-id=\"9e37ef4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c5ad8b7 e-con-full e-flex e-con e-child\" data-id=\"c5ad8b7\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-804813b elementor-widget elementor-widget-heading\" data-id=\"804813b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Surface Reimagined: A Scalable Coating for Consistent 3D Cell Modeling<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76b8106 elementor-widget elementor-widget-text-editor\" data-id=\"76b8106\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Jan St\u00e5lemark<br \/><\/strong>CEO and Co-founder<br \/>Cell2Bio<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a17e79 elementor-widget elementor-widget-text-editor\" data-id=\"3a17e79\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: justify;\"><span lang=\"RO\">Three-dimensional (3D) cell cultures have emerged as essential models for studying tissue physiology and disease due to their superior ability to recapitulate native architecture and function. However, conventional techniques to induce 3D growth present significant limitations. Anchorage-independent growth on ultra-low attachment (ULA) surfaces relies on random aggregation, often yielding heterogeneous spheroid sizes and lacking the natural cell\u2013extracellular matrix (ECM) interactions of native tissues. Conversely, hydrogel encapsulation supports 3D tissue architectures but restricts nutrient diffusion, cell retrieval, and downstream processing. Robust and reproducible induction of 3D growth across diverse substrates thus remains challenging.<\/span><\/p><p style=\"text-align: justify;\"><span lang=\"RO\">Here, we present a cellulose nanofibril (CNF)-based bioactive coating capable of transforming conventional two-dimensional (2D) surfaces into platforms that reliably support 3D cellular growth. The CNF coating facilitates the spontaneous formation of multicellular spheroids and network-like aggregates across a range of adherent cell types. Time-lapse microscopy revealed that local interactions between cells and the CNF coating simulate ECM-like adhesion, enabling the transition from 2D monolayers to compact 3D assemblies within the first 24 hours. This process results in uniform spheroid formation driven by both proliferation and intrinsic spatial organization. Unlike existing technologies, our platform integrates natural-like 3D architecture without embedding, permitting unhindered nutrient exchange and straightforward downstream analysis.<\/span><\/p><p style=\"text-align: justify;\"><span lang=\"RO\">The coating\u2019s composition and application protocol are compatible with various materials and existing culture formats, including microfluidic chips. These properties enable broad use in long-term 3D culture, tumor and organ-on-a-chip models, drug screening, and tissue engineering applications.<\/span><\/p><p><em>Jan St\u00e5lemark is a Swedish life-science executive and entrepreneur with 30+ years of international MedTech and HealthTech leadership. He is Co-Founder &amp; CEO of Cell2Bio and Founder&amp; CEO of HealthTech Sweden. Jan has led multiple companies through his career, driving growth, clinical adoption, and capital raises.\u00a0<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2e39d6e elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile e-flex e-con-boxed e-con e-parent\" data-id=\"2e39d6e\" data-element_type=\"container\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c4927a6 e-con-full e-flex e-con e-child\" data-id=\"c4927a6\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-8cfd28c e-flex e-con-boxed e-con e-child\" data-id=\"8cfd28c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c58761f elementor-widget elementor-widget-text-editor\" data-id=\"c58761f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d89a4f elementor-widget elementor-widget-image\" data-id=\"1d89a4f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"308\" height=\"308\" src=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Oana-Tudoran.jpg\" class=\"attachment-1536x1536 size-1536x1536 wp-image-1934\" alt=\"\" srcset=\"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Oana-Tudoran.jpg 308w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Oana-Tudoran-300x300.jpg 300w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/Oana-Tudoran-150x150.jpg 150w, https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-content\/uploads\/sites\/8\/2025\/12\/elementor\/thumbs\/Oana-Tudoran-150x150.jpg 500w\" sizes=\"(max-width: 308px) 100vw, 308px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-90c7e9c e-con-full e-flex e-con e-child\" data-id=\"90c7e9c\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c705152 elementor-widget elementor-widget-heading\" data-id=\"c705152\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Surface Reimagined: A Scalable Coating for Consistent 3D Cell Modeling<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1fbc929 elementor-widget elementor-widget-text-editor\" data-id=\"1fbc929\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Oana Tudoran<br \/><\/strong>Research Manager<br \/>Cell2Bio<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f1b0705 elementor-widget elementor-widget-text-editor\" data-id=\"f1b0705\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: justify;\"><span lang=\"RO\">Three-dimensional (3D) cell cultures have emerged as essential models for studying tissue physiology and disease due to their superior ability to recapitulate native architecture and function. However, conventional techniques to induce 3D growth present significant limitations. Anchorage-independent growth on ultra-low attachment (ULA) surfaces relies on random aggregation, often yielding heterogeneous spheroid sizes and lacking the natural cell\u2013extracellular matrix (ECM) interactions of native tissues. Conversely, hydrogel encapsulation supports 3D tissue architectures but restricts nutrient diffusion, cell retrieval, and downstream processing. Robust and reproducible induction of 3D growth across diverse substrates thus remains challenging.<\/span><\/p><p style=\"text-align: justify;\"><span lang=\"RO\">Here, we present a cellulose nanofibril (CNF)-based bioactive coating capable of transforming conventional two-dimensional (2D) surfaces into platforms that reliably support 3D cellular growth. The CNF coating facilitates the spontaneous formation of multicellular spheroids and network-like aggregates across a range of adherent cell types. Time-lapse microscopy revealed that local interactions between cells and the CNF coating simulate ECM-like adhesion, enabling the transition from 2D monolayers to compact 3D assemblies within the first 24 hours. This process results in uniform spheroid formation driven by both proliferation and intrinsic spatial organization. Unlike existing technologies, our platform integrates natural-like 3D architecture without embedding, permitting unhindered nutrient exchange and straightforward downstream analysis.<\/span><\/p><p style=\"text-align: justify;\"><span lang=\"RO\">The coating\u2019s composition and application protocol are compatible with various materials and existing culture formats, including microfluidic chips. These properties enable broad use in long-term 3D culture, tumor and organ-on-a-chip models, drug screening, and tissue engineering applications.<\/span><\/p><p><em>Oana-Mihaela Tudoran is a translational cancer scientist specializing in platform creation at the interface of tumor biology and emerging technologies. With over 15 years of experience in clinical cancer research she has built and operationalized new capabilities that integrates advanced 3D models, transcriptomic profiling, and microfluidic technologies to uncover the mechanisms of tumor progression and treatment resistance Her work dissects how tumor\u2013stroma interactions drive progression, immune evasion, and stem-like behavior, always with a clear route to clinical deployment. Oana has led high-stakes, multi-institution collaborations across academia, hospitals, and industry, pushing teams to move beyond incremental improvement toward functional innovation with real translational impact.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Note: Speaker recruitment is currently ongoing. The list of speakers is subject to continuous updates and additions.\u00a0 Moderator Johan RockbergProfessor in Antibody Technology and Directed EvolutionKTH Royal Institute of Technology Johan Rockberg is Professor of Antibody Engineering and Directed Evolution at KTH &#8211; Royal Institute of Technology in Stockholm, Sweden. He holds a Master of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"_links":{"self":[{"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/pages\/742"}],"collection":[{"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/comments?post=742"}],"version-history":[{"count":181,"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/pages\/742\/revisions"}],"predecessor-version":[{"id":2266,"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/pages\/742\/revisions\/2266"}],"wp:attachment":[{"href":"https:\/\/nmevents.se\/bioprocessing-stockholm\/wp-json\/wp\/v2\/media?parent=742"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}